TESCAN’s SEMs help with pioneering research in reproductive medicine. In the first study investigating the ultrastructure of human oocytes in 3D, FIB/SEM tomography gave an unprecedented view of ooplasmic architecture. Researchers were able to explore spatial relationships between intracellular components and track structural changes associated with cytoplasmic maturation in oocytes in various developmental stages using TESCAN’s AMBER, AMBER X, and SOLARIS X instruments. The findings are highly significant for reproductive medicine and demonstrate the potential of large volume electron microscopy to study rare and delicate samples such as female gametes.
“High-Resolution 3D Reconstruction of Human Oocytes Using Focused Ion Beam Scanning Electron Microscopy,” published on November 2 in Frontiers in Cell and Developmental Biology by Zuzana Trebichalská¹, Jakub Javůrek², Martina Tatíčková¹, Drahomíra Kyjovská³, Soňa Kloudová³, Pavel Otevřel³, Aleš Hampl¹ and Zuzana Holubcová₁,₃*
¹ Department of Histology and Embryology, Faculty of Medicine, Masaryk University, Brno, Czechia
² TESCAN ORSAY HOLDING, a.s., Brno, Czechia
³ Reprofit International, Brno, Czechia
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