Versatile UHR SEM for characterization of your biological beam sensitive samples in 2D and 3D

TESCAN CLARA is an Ultra High Resolution Scanning Electron Microscope (UHR-SEM) with a Field Emission Gun electron source that allows users to examine the microstructure, morphology and surface characteristics of biological (and other) samples across research fields. TESCAN CLARA is well suited for a variety of demanding SEM applications such as high resolution and low energy imaging, and volume EM techniques, and is compatible with cryo workflows. It is an ideal tool for busy imaging centers that are looking for an instrument with outstanding imaging performance together with the flexibility to cover a wide range of research tasks. The ability to switch rapidly between different operating modes is important for the productivity of microscopy facilities.


  • Imaging from overview to the nanoscale – and everything in-between Unique UHR-SEM optics design gives TESCAN CLARA unmatched versatility
  • Image non-conductive beam-sensitive biological samples at extremely low beam energies Benefit from UHR BrightBeam™ column technology that delivers sharp images even at low voltages
  • Generate high-contrast images with nanoscale details. The powerful combination of the BrightBeam™ column & detection system allows charge-free topographic imaging

  • Extend your SEM to perform Volume SEM analysis Integrated Serial Block-Face SEM (SBF-SEM) in-chamber microtome and Array Tomography software module allow large volume analysis of samples
  • Perform your experiments at ambient and/or cryogenic temperatures
  • The unmatched versatility of TESCAN CLARA design fits the needs of most users in core facilities or other research institutes

TESCAN Webinars:

TESCAN SEM & FIB-SEM solutions optimized for your Life Science applications

SEM Large-volume Analysis in Life Sciences assisted by Serial Block-Face Imaging

  • Application note

    SEM - Taxonomic determination of rare biological specimen

    pdf 3 MB Download
  • Application note

    CryoSEM - Understanding the origin and progression of fungal disease

    pdf 2 MB Download
  • Application note

    SBFI - Large area 3D volume reconstruction of Flatworm body

    pdf 2 MB Download
  • Application note

    SEM - Characterisation of microbial isolate

    pdf 448 KB Download
  • Application note

    SEM - Investigation of drug encapsulation

    pdf 385 KB Download
  • Application note

    SEM - Taxonomic determination of small organisms-ticks

    pdf 954 KB Download
  • Application note

    SEM observation of sperm entering the oocyte

    pdf 355 KB Download
  • Application note

    STEM - Immunohistochemical localization of tumor cells

    pdf 359 KB Download
  • Application note

    STEM - Investigation of liposomal nanoparticles using high-resolution SEM

    pdf 454 KB Download
  • Product flyer

    TESCAN Essence Colision Model

    pdf 195 KB Download
  • Product flyer

    TESCAN Wide Field Mode

    pdf 239 KB Download
Get in touch

Do you wish to discuss TESCAN CLARA cryo solution? Contact our Team directly!